Coturnix japonica/Gallus gallus/Pavo cristatus
Danio rerio
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Danio rerio
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Xenopus laevis
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Ambystoma mexicanum
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Orgel's First Rule: Whenever a spontaneous process is too slow or too inefficient a protein will evolve to speed it up or make it more efficient.” — Leslie Eleazer Orgel |
With a focus on identifying localization of endogenous proteins and determining how perturbation of those proteins affects cranial neural crest cell formation, migration, and differentiation, we can begin to unravel the molecular mechanisms that make the cells that make faces. Our goal is to perform comparative functional analyses using multiple vertebrate species to identify similarities and differences in developmental processes.
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